4-Nitro-3-phenylphenol has both androgenic and anti-androgenic-like effects in rats
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4-Nitro-3-phenylphenol has both androgenic and anti-androgenic-like effects in rats
To investigate the effect of endocrine disruption of 4-nitro-3-phenylphenol (PNMPP) on immature male Wistar-Imamichi rats, the rat pituitary was exposed to PNMPP (10(-5)-10(-9) M) for 24 h with or without gonadotropin-releasing hormone (GnRH) in experiment I. In addition, the Leydig cells (10(-5)-10(-9) M) were exposed to PNMPP for 24 h with or without human chronic gonadotropin (hCG) in experi...
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ژورنال
عنوان ژورنال: Journal of Reproduction and Development
سال: 2015
ISSN: 0916-8818,1348-4400
DOI: 10.1262/jrd.2014-110